YOUNG SCIENTISTS' SCHOOL PROGRAM:
Day 1 - September 10, Monday
Primer on stem cell models for bench research - Prof. Diane Barber, USA
New views on the cell biology of stem cells
a. Mulas et al., NODAL and formative pluripotency. Stem cell reports 2017.
b. Acampora et al., Functional antagonism between OTX2 and NANOG specifies a spectrum of heterogeneous identities in embryonic stem cells. Stem cell reports 2017.
Day 2 - Septemtber 11, Tuesday
Bacterial morphogenesis - Dr. Haig Eskandarian, Switzerland
Bacterial morphogenesis – continuation
a. Wu & Errington. Use of asymmetric cell division and spoIIIE mutants to probe chromosome orientation and organization in Bacillus subtilis. Mol Micro. 1998.
b. Frandsen, Barak, Karmazyn-Campelli, Stragier. Transient gene asymmetry during sporulation and establishment of cell specificity in Bacillus subtilis.Genes & Dev. 1999.
c. Higgins & Dworkin. Recent progress in Bacillus subtilis sporulation. FEMS Microbiology Reviews 2012.
Day 3 - September 12, Wednesday
Human Genetics and the Concept of Disease –
Prof. Eberhard Passarge
a. Gonen et al. Sex reversal following deletion of a single distal enhancer of Sox9. Science 2018.
b. Sumantra Chatterjee et al., Enhancer variants synergistically drive dysfunction of a gene regulatory network in Hirschsprung disease. Cell 2016.
Day 4 - September 13, Thursday
Open discussion with participants