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LABORATORY OF CELL BIOLOGY AND VIROLOGY
HEAD:
Zaven Karalyan, PhD, DrSc, Professor
E-mail: zkaralyan@yahoo.com
Phone(off): +374 10 281-626
FAX: +374 10 282-061
Lab members:
General information:
Since its inception the laboratory of cellular biology and virology engaged in the research of cytological status of the various
primary, secondary and transplantable cell lines during cultivation and the influence of various drugs and biologically active substances, as well
as viruses, on cells.
Subsequently, in the laboratory began to study the pathogenesis of viruses in vivo and in vitro conditions. The objects of interest
are picornaviruses (poliovirus, encephalomyocarditis and FMDV) and African swine fever virus (genotype 2).
For in vitro researches laboratory has a large bank of cultivating cell lines such as Hela, BHK, RD, Vero, Cos, etc.
In the last few years the laboratory has been actively working on the study of the African swine fever (ASF) virus which is distributes on the territory
of Armenia and neighboring Georgia. Clinical picture and pathology of blood and bone marrow in the ASF genotype 2 fully investigated.
A new direction in the activities of the laboratory are study of ASF virus genotype 2 complete genome, the phylogenetic definition of ASF virus (genotype 2),
as well as epigenetic changes in the genome.
Current research projects:
">To date, the laboratory was investigating:
- Molecular mechanisms of the pathogenesis of African swine fever (ASF) in the in vivo and in vitro conditions;
- Investigation of possible reservoirs of the African swine fever virus;
- Studying phylogeny of African swine fever virus genotype 2;
- Research of bioactive substances and chemical molecules for antiviral activity.
Selected Publications:
>> Full publications list of IMB