Immunoblotting of C3 component of the complement in cryoglobulins (Laboratory of Macromolecular Complexes)

C3 in an important component of complement system, and for the first time C3 and its split components were observed in cryoglobulins isolated from the blood of schizophrenia patients.

Quantitative distribution of nucleic acids in RD cell line (Laboratory of Cell Biology).

Nucleuic acid distribution in cells is an important characteristic of physiological state of the cell under persistent picornoviral infection.

The Young Scientists Conference "Perspectives for Development of Molecular and Cellular Biology"

Three young scientists received honorary awards from organizing commitee

HAPPY NEW YEAR

Dear colleagues and friends,

We wish you peaceful and happy New Year with

lot of fun and love, good health and prosperity.

Sincerely,
Institute of Molecular Biology NAS RA

Fields of Activity

Research activities of the Institute are focused on investigation of regulatory mechanisms of cell activity and alterations in cell activity in a number of pathologic conditions including autoimmune, autoinflammatory, infectious, acute inflammatory, oncological, and psychiatric disorders. The research includes human, animal and cell-cultures studies on genetic, cellular, membrane, sub-cellular and immune-system levels. Prospective practical outcomes of these studies are:

• identification of vital biological markers of pre-diseased and diseased conditions, disease progression and outcome;
• development of the efficient therapeutic approaches based upon application of new bioactive compounds, cell-activity modulators.

Application areas of the research results mainly include molecular diagnostics and prognostics of diseases, and new drug design. The Institute holds several patents relating to new bioactive compounds.

Recently defended PhD theses

1. Elina Arakelova. Molecular pathomechanisms of the development of inflammatory response and its association with the state blood brain barrier in acute ischemic stroke. Yerevan, 2011. Supervisor: Anna Boyajyan, Prof.
2. Gayane Ghazaryan. Oxidative processes and metabolism of glycolphospholipids in the brain in experimental Parkinson’s syndrome. Yerevan, 2011. Supervisor: Laura Hovsepyan, PhD.
3. Nelly Babayan. New synthetic porphyrins as anticancer agents: in vitro study of structure-function interconnection. Yerevan, 2011. Supervisor: Rouben Aroutiounian, Prof., corr. member NAS RA
4. Mihran Lazyan. Lipid modifications and signal transduction mechanisms in blood lymphocytes in breast cancer. Yerevan, 2011. Supervisor: Yuri Tadevosyan, Prof. Laris Andonian. Comparative investigation of Y-chromosome variability in some ethnic groups living in Iran. Yerevan, 2011. Supervisor: Levon Yepiskoposyan, DrSc.
5. Arkadi Manukyan. G1 phase cyclins, cell growth and regulation of cell size. Yerevan, 2010. Supervisor: Karen Nazaryan, DrSc.
6. Study of cytological state of cells of different transplantable human and animal tissue cultures, their classification and cluster analysis. Yerevan, 2010. Supervisor: Zaven Karalyan, Prof.
7. Aren Khoyetsyan. The role of the mediators of immune response in the pathogenesis of schizophrenia. Yerevan, 2008. Supervisor: Anna Boyajyan, Prof.
8. Gayane Manukyan. Molecular aspects of immune response in familial Mediterranean fever. Yerevan, 2008. Supervisor: Karine Ghazaryan, PhD.
9. Levon Manukyan. The structural and functional role of the complement system and cryoglobulins in post-ischemic immune response progression in human ischemic stroke. Yerevan, 2007. Supervisors: Anna Boyajyan, Prof., Violeta Ayvazyan, PhD.
10. Zaruhi Khachatryan. Gut microflora composition in Familial Mediterranean Fever. Yerevan, 2007. Supervisors: Zhanna Ktsoyan, PhD, Rustam Aminov, Prof.
11. Gohar Hakobyan. Lymphocyte-associated signal transduction and lipid modification mechanisms in patients with acute lymphoblastoma. Yerevan, 2007. Supervisor: Yuri Tadevosyan, Prof.
12. Margarita Melkonyan: Lymphocyte-associated signal transduction and lipid modification mechanisms in patients with acute myeloblastoma. Yerevan, 2007. Supervisor: Yuri Tadevosyan, Prof.
13. Gohar Mkrtchyan. Circulating immune complexes and the classical pathway of complement activation in Familial Mediterranean Fever. Yerevan, 2006. Supervisor: Anna Boyajyan, Prof.
14. Lina Poghosyan. Purinenucleotide phosphorilase from human tumors and its inhibitors. Yerevan, 2006. Supervisor: Zhan (J.) Akopian, Prof., corr. member NAS RA
15. Svetlana Hakobyan. Immune complexes and the classical pathway of complement activation in schizophrenia. Yerevan, 2005. Supervisor: Anna Boyajyan, Prof.

Training & Education

For decades IMB is hosting many prospective young scientists, under- and postgraduates and post-Docs. Dedicated researchers supervise interested thesis students. The graduate and undergraduate students hosted by IMB are exposed to research within the area of the basic sciences, and in related emerging disciplines.

From 2006 IMB is facilitating the Department of Biotechnology (Head Anna Boyajyan, Prof.) of the International Scientific and Educational Center NAS RA providing master degree course in biotechnology.

From 2007 IMB also facilitates trainings on basic and advance methods of biomedical research organized for students of Biomedical Faculty of Russian- Armenian (Slavonic) State University.
 
 

ANNOUNCEMENTS

The Institute of Molecular Biology NAS RA

is organizing a Course of Lectures for young scientists (beginning from bachelor degree) “Molecular and Immunological Bases of Host-Microbes Interactions” to be hold in October 3-7, 2011 in Yerevan, Armenia.

Participation is free of charge.
Click here for registration

International young scientists conference "Perspectives for development of molecular and cellular biology II"

10-12 November, Yerevan, Armenia

Dear colleagues,
The Institute of Molecular Biology NAS RA is pleased to inform that the International Young Scientists Conference “Perspectives for Development of Molecular and Cellular Biology-2” successfully finished.

The International Scientific and Educational Center of the National Academy of Sciences of the Republic of Armenia (NAS RA) and the Institute of Molecular Biology NAS RA

welcome applications from foreign students, who wish:

1. to enter 2-year Master’s Course in Biotechnology starting from mid September 2008 and facilitating by the Institute of Molecular Biology NAS RA (www.molbiol.sci.am).
The deadline for submitting application is September 30, 2010.

2. to conduct their PhD study in the Institute of Molecular Biology NAS RA. Prospective students may conduct there research in the following areas of molecular and cellular biology  (see here detailed information).

For detailed information regarding eligibility criteria, necessary documents, and other requirements, etc, please contact to Director of Institute of Molecular Biology NAS RA, prof. Anna Boyajyan. (Contact details)

International conference “Prospects of haematology and transfusiology development” devoted to the 75 anniversary of fundation of the Hematological centre after prof. R.H. Yeolyan

Dear colleagues and friends!
We are pleased to invite you to take part in the International Scientific-Practical Conference “Prospects of hematology and transfusiology development”, devoted to the 75th anniversary of foundation of the Hematological Centre after prof. R.H. Yeolyan of the Ministry of Health of the Republic of Armenia. The Conference will take place on October 9-10, 2008 in Yerevan.
Contact Person: Lusine Sahakyan Organizing committee, “Hematological Centre after Prof. R.Yeolyan” Ministry of Health of the Republic of Armenia 7, G.Nersisyan str.0014,Yerevan, RA
Phone: +374 10 283890
Fax: +374 10 284478
E-mail: haemconference@blood.am,
           haemconference@gmail.com
(see here detailed information on Russian and English).